After splenectomy, patients are at increased risk for which type of infections?

After splenectomy, patients are at increased risk for which type of infections?

• A. Minor infections only
• B. No infection risk
• C. Lifelong infections
• D. Transient infections

Answer: (C)

The spleen protects against infections, especially from encapsulated bacteria, by filtering bacteria from the blood and producing IgM-rich, opsonizing antibodies that help macrophages clear invaders. When the spleen is removed, this specific immune defense is lost, so the risk of serious, potentially life-threatening infections from encapsulated organisms remains for life. That’s why lifelong vigilance is needed, not just a temporary or minor risk. Vaccinations against pneumococcus, Haemophilus influenzae type b, and meningococcus are essential, and some patients may require preventive antibiotics in certain situations. If a fever develops, urgent evaluation is important due to the ongoing infection risk.

The spleen protects against infections, especially from encapsulated bacteria, by filtering bacteria from the blood and producing IgM-rich, opsonizing antibodies that help macrophages clear invaders. When the spleen is removed, this specific immune defense is lost, so the risk of serious, potentially life-threatening infections from encapsulated organisms remains for life. That’s why lifelong vigilance is needed, not just a temporary or minor risk. Vaccinations against pneumococcus, Haemophilus influenzae type b, and meningococcus are essential, and some patients may require preventive antibiotics in certain situations. If a fever develops, urgent evaluation is important due to the ongoing infection risk.