Rapid acting insulin peak (aspart, lispro, glulisine) is typically:

Rapid acting insulin peak (aspart, lispro, glulisine) is typically:

• A. 30mins-3 hours
• B. 1-2 hours
• C. 4-6 hours
• D. 6-8 hours

Answer: (A)

Rapid-acting insulins have a quick onset to match a meal, with the strongest glucose-lowering effect occurring in the first part of their action. The peak is typically reached within the first couple of hours after injection, and many references describe this peak window as roughly 30 minutes to 3 hours. That broader range best fits the actual time frame when aspart, lispro, and glulisine exert their maximum effect, which is why it’s the best description among the options. To put it in context, the onset of rapid-acting insulin is around 10–20 minutes after injection, with peak activity around 1–2 hours (and up to about 3 hours in some sources), and a total duration of roughly 3–5 hours. The other windows—4–6 hours or 6–8 hours—are too long for this insulin’s peak, and a narrower 1–2 hour window doesn’t capture the full commonly cited peak range.

Rapid-acting insulins have a quick onset to match a meal, with the strongest glucose-lowering effect occurring in the first part of their action. The peak is typically reached within the first couple of hours after injection, and many references describe this peak window as roughly 30 minutes to 3 hours. That broader range best fits the actual time frame when aspart, lispro, and glulisine exert their maximum effect, which is why it’s the best description among the options.

To put it in context, the onset of rapid-acting insulin is around 10–20 minutes after injection, with peak activity around 1–2 hours (and up to about 3 hours in some sources), and a total duration of roughly 3–5 hours. The other windows—4–6 hours or 6–8 hours—are too long for this insulin’s peak, and a narrower 1–2 hour window doesn’t capture the full commonly cited peak range.