Some antibiotics ending with the suffix -cin can cause which of the following adverse effects?

Some antibiotics ending with the suffix -cin can cause which of the following adverse effects?

• A. Prolonged QT Interval
• B. Nephrotoxicity
• C. Hyperkalemia
• D. Prolonged QT Interval and Hepatotoxicity

Answer: (D)

Antibiotics ending with -cin are mainly macrolides, a class known to affect heart rhythm and the liver. They can prolong the QT interval, which raises the risk of dangerous arrhythmias like torsades de pointes, especially with electrolyte disturbances or other QT‑prolonging drugs. They can also cause hepatotoxicity, evidenced by elevated liver enzymes or cholestatic liver injury in some patients. Because this group is associated with both QT prolongation and hepatotoxicity, that combination best matches the adverse effects described. Nephrotoxicity and hyperkalemia are not typical primary risks of this class.

Antibiotics ending with -cin are mainly macrolides, a class known to affect heart rhythm and the liver. They can prolong the QT interval, which raises the risk of dangerous arrhythmias like torsades de pointes, especially with electrolyte disturbances or other QT‑prolonging drugs. They can also cause hepatotoxicity, evidenced by elevated liver enzymes or cholestatic liver injury in some patients. Because this group is associated with both QT prolongation and hepatotoxicity, that combination best matches the adverse effects described. Nephrotoxicity and hyperkalemia are not typical primary risks of this class.