What is the primary action of ACE inhibitors?

What is the primary action of ACE inhibitors?

• A. Increase heart rate
• B. Dilate blood vessels
• C. Decrease respiratory rate
• D. Promote diuresis

Answer: (B)

ACE inhibitors work by blocking the conversion of angiotensin I to angiotensin II, a powerful vasoconstrictor. With less angiotensin II, blood vessels dilate, reducing systemic vascular resistance and blood pressure. This vasodilatory effect is the main mechanism by which these drugs lower BP and help in heart failure. A secondary effect is reduced aldosterone secretion, which can promote some diuresis, but that diuretic effect is not the primary action. They do not directly increase heart rate or alter respiratory rate.

ACE inhibitors work by blocking the conversion of angiotensin I to angiotensin II, a powerful vasoconstrictor. With less angiotensin II, blood vessels dilate, reducing systemic vascular resistance and blood pressure. This vasodilatory effect is the main mechanism by which these drugs lower BP and help in heart failure. A secondary effect is reduced aldosterone secretion, which can promote some diuresis, but that diuretic effect is not the primary action. They do not directly increase heart rate or alter respiratory rate.