Which statement about ketorolac is true?

Which statement about ketorolac is true?

• A. It can be used for chronic pain management
• B. It should not exceed 5 days due to risks of kidney injury, GI ulcers, and bleeding
• C. It has no effect on kidney function
• D. It is safe for patients with GI ulcers

Answer: (B)

Ketorolac is a potent NSAID used for short-term relief of moderate to severe acute pain. The key idea is that its safety window is limited because of serious risks to the kidneys and the GI tract. NSAIDs inhibit prostaglandin synthesis, which helps maintain renal perfusion and protects the stomach lining. When these prostaglandins are reduced, kidney function can be compromised and GI ulcers or bleeding can occur, especially with longer use. Because of these risks, ketorolac should be limited to about five days of therapy in adults. It is not appropriate for chronic pain management, it can affect kidney function, and it is not safe for patients with GI ulcers.

Ketorolac is a potent NSAID used for short-term relief of moderate to severe acute pain. The key idea is that its safety window is limited because of serious risks to the kidneys and the GI tract. NSAIDs inhibit prostaglandin synthesis, which helps maintain renal perfusion and protects the stomach lining. When these prostaglandins are reduced, kidney function can be compromised and GI ulcers or bleeding can occur, especially with longer use. Because of these risks, ketorolac should be limited to about five days of therapy in adults. It is not appropriate for chronic pain management, it can affect kidney function, and it is not safe for patients with GI ulcers.